HSP90B2P and amyotrophic lateral sclerosis: Using digital precision and real-time thermoregulatory feedback, CBIT2 was employed to induce heat shock protein (HSP) in the brain, specifically targeting motor neurons, with the aim of counteracting a biomarker-confirmed trajectory of rapid disease progression and impending demise in the patient while reversing neurodegeneration and overcoming the well-documented limitations of existing ALS therapies.