The results showed that a maximal LH response at 3 h after Triptorelin administration ≥ 7 IU/L (by IFMA) or ≥8 IU/L (by ECLIA) diagnosed CPP with a specificity of 100% (95% CI: 75–100%) and a sensitivity of 76% (95% CI: 58–89%). The gene discussed is PLOD1; the disease is central precocious puberty.