Furthermore, emerging evidence has remarked that molecules involved in the onset of osteoporosis, such as Vitamin D, Osteocalcin, Osteopontin, Parathyroid hormone (PTH), and sclerostin (s) [12,13,14,15,16] may influence Aβ plaque formation, senescence, apoptosis and inflammation of nerve cells, as well as synaptic plasticity. This evidence concerns the gene PTH and osteoporosis.