IL6 and neoplasm: Mechanistic models align with these observations: high-dose antibiotics induced dysbiosis, accelerated OC growth, enhanced TNF-α and IL-6 secretion from tumor-associated macrophages, promoted EMT and angiogenesis, and expanded cancer stem-like cells; dysbiosis also exacerbates cisplatin resistance, whereas FMT from untreated donors restores chemosensitivity [80,102,103].