FTH1 and neoplasm: Anlotinib, a multikinase antiangiogenic inhibitor, was shown to suppress ATC cell proliferation and metastasis by activating the autophagy–ferroptosis axis and downregulating GPX4, ferritin heavy chain (FTH1), and heme oxygenase-1 (HO-1), while protective autophagy blockade further amplified ferroptosis and enhanced tumor regression [12].