The highest CFSE fluorescence signals and highest Iba1+ fluorescence signals were recorded in animals that received sTDEVs released by H-FIRE-treated glioma cells, while the lowest CFSE fluorescence signals and lowest Iba1+ fluorescence signals were recorded in animals that received sTDEVs released by 0 V/cm-treated glioma cells (Figure 7C). The gene discussed is AIF1; the disease is glioma.