In the tumor zone outside the nerve identified by the tumor cell’s distinctive large blue nuclei, shown in H&E staining, as well as the lacking of NF200 or MPZ nerve markers, we found that the tumor microenvironment exhibited an increased number for FOXP3+/CD4+ Tregs (Figure 4A,B), CD4+ T cells (Figure 4A or Figure 4C), CD8+ T cells (Figure 4D,E), Ly6G+ neutrophils (Figure 4H,I), CD11b+/F4/80−/Ly6C− (Figure 4J,K), and Ly6C+/CD11b−/F4/80− (Figure 4J or Figure 4L) cells. Here, CD4 is linked to neoplasm.