An ultrasensitive immunosensor for asthma biomarker thymic stromal lymphopoietin (TSLP) by integrating a dual-luminescent T-COF constructed from AIE-active monomer and 9,10-anthracenedicarboxaldehyde units into a microfluidic chip and pairing it with camel-derived nanobodies [65]. The gene discussed is TSLP; the disease is asthma.