MIF and colorectal carcinoma: Recent studies have shown that MIF also plays a significant role in the occurrence, progression, and resistance of several solid tumors [8,17] including head and neck [18], lung, breast, prostate, cervical, hepatocellular, gastric, esophageal, glioblastoma, renal, pancreatic, neuroblastoma, melanoma, ovarian cancer [19], and CRC [5,8,20,21].