Moreover, the use of SERPINA1 has been statistically studied in a cohort of 15 CRC, 15 adenomas, 15 healthy controls with a validation test of 19 CRC patients and 21 healthy controls, obtaining 95% of sensitivity and specificity, an AUC of 0.97 with a cu-off value un serum of 817 μg mL−1. The gene discussed is SERPINA1; the disease is colorectal carcinoma.