Although several genes such as BRCA1, XRCC4/6, and FANCM are established biomarkers in pancreatic ductal adenocarcinoma (PDAC), they were not included in the present analysis, as the pathogenic BRCA2 variant identified in our cohort represents the first and only molecular feature linking pNENs to PDAC biology. The gene discussed is FANCM; the disease is pancreatic ductal adenocarcinoma.