KRAS and colorectal carcinoma: To investigate the functional specificity of KRAS mutations (G12V, G12D, or G13D) in CRC, particularly the variability between the codon 13 and codon 12 KRAS mutants, Hammond et al. employed a SILAC-based quantitative approach to analyze the proteome and phosphoproteome of isogenic KRAS mutant SW48 CRC cell lines.