Bioinformatic analysis, particularly in atopic dermatitis, identified the essential genetic targets of miRNA-26a, such as hyaluronan synthase 3 (HAS3) and also CHAC1, while in asthma, miRNA-26a influenced SMAD2,3 and TGF-β-related signaling pathways [1,8,37,44,124,125,126]. The gene discussed is TGFB1; the disease is asthma.