In OLP, cytotoxic CD8+ T cells induce keratinocyte apoptosis at the epithelial–connective tissue interface, while in MMP and PV, autoantibody binding against basement membrane components or desmogleins produces subepithelial or intraepithelial blistering [1,2,3,5,74,75,76]. The gene discussed is CD8A; the disease is oral lichen planus.