This phenomenon is attributable to AF alterations caused by non-neoplastic conditions: inflammation, trauma, and vascular changes often increase submucosal hemoglobin content or alter fluorophore concentrations (collagen, NADH, FAD, porphyrins, elastin, keratin), producing AF patterns that mimic dysplasia or carcinoma [26,58]. The gene discussed is ELN; the disease is dysplasia.