Total thyroidectomy can lead to hypoparathyroidism, the most frequent complication, with an incidence of permanent hypoparathyroidism of 4.11% at 6 months postoperatively.6 Low postoperative levels of PTH and the resulting hypocalcemia may be associated with the accidental removal of one or more glands or compromised blood supply. This evidence concerns the gene PTH and hypoparathyroidism.