LINC01605 is upregulated in a mouse model of aortic dissection and participates in the cellular processes of migration, proliferation and autophagy associated with aortic dissection by modulating the expression of genes such as SGK1, MMP‐2, MMP‐9, α‐SMA, SM22α, LC3B and p62. The gene discussed is MMP2; the disease is Aortic dissection.