F5 and deep vein thrombosis: In the realm of genetics, epidemiological studies in Brazil, such as one conducted in the state of Minas Gerais, emphasize the importance of genetic tests for identification of individuals at risk and for effective clinical management of thrombosis and CVD.34 Presence of genetic mutations, such as factor V Leiden and the G20210A mutation of the prothrombin gene, combined with hormonal and physiological factors associated with pregnancy, also contribute to increased risk of venous thrombosis among women.34