Wu et al. reported that downregulation of the long non-coding RNA (lncRNA) nuclear paraspeckle assembly transcript 1 (NEAT1) attenuates MI of mice via the miR-582-5p/Coagulation factor II thrombin receptor like 2 (F2RL2) axis (Wu et al., 2022). The gene discussed is NEAT1; the disease is myocardial infarction.