For instance, BTBD7 plays a role in the development of multiple tumors (7); BTBD3 inhibits colorectal cancer tumorigenesis by regulating the TYRO3/Wnt/β-catenin signaling axis; MiR-200b-5p suppresses tumor progression in salivary adenoid cystic carcinoma by targeting BTBD1 (8); and BTBD10 inhibits glioma tumorigenesis by downregulating cyclin D1 and p-Akt9. Here, BTBD1 is linked to neoplasm.