(83) further confirmed the anti-inflammatory effects of IL-37 in an OVA-induced asthma model, showing that transgenic mice expressing IL-37a and IL-37b had a significant reduction in eosinophils in the lungs, with a minor increase in neutrophils and no significant changes in lymphocyte and macrophage counts compared to wild-type mice. The gene discussed is IL37; the disease is asthma.