Interestingly, recent work in AD mouse models demonstrated that transplantation of TET2-mutant, but not DNMT3A-mutant, bone marrow-derived cells reduced cognitive decline and Aβ production, suggesting a causal association between TET2-mutations, clonal hematopoiesis, and cognitive resilience (Matatall et al., 2025). The gene discussed is TET2; the disease is Mental deterioration.