IL6 and 22q11.2 deletion syndrome: Individuals with 22q11DS demonstrate elevated levels of cytokines, including interleukin-12 (IL-12), IL-6, the IL-6/IL-10 ratio, IP-10, and TNF-α; and some of these cytokines corelate with autistic behaviors in these patients (Ross et al., 2013, Aresvik et al., 2016, Mekori-Domachevsky et al., 2017, Frusone et al., 2024).