Tid, a GSK-3β inhibitor, has positive effects on several types of CNS diseases (Horrigan et al. 2020; MARTíNEZ-GONZáLEZ et al. 2021; Bahmad et al. 2021) and has been shown to have antiapoptotic effects and inhibit astrocyte activation during hypoxic brain injury in newborn mice (Wang et al. 2016). This evidence concerns the gene GSK3B and brain injury.