MAPT and Alzheimer disease: P2X7R levels were also positively correlated with p-tau (AT-8) levels in AD patients and NCs (p = 0.0241, r = 0.2941 in CA1; p = 0.0347, r = 0.2737 in CA2/3; p = 0.0416, r = 0.2620 in the DG) (Fig. 5f, SFig. 5d, e).