The group with severe infection had greater values for WBC, AMC, PLT, CRP, ALT, GGT, creatinine, uRBCs, 24 h urine protein, cystatin C, LDH, corrected serum calcium, APTT, D-dimer, and IgE, used more types of immunosuppressants, and had a higher incidence of SRNS. This evidence concerns the gene IGHE and infection.