Furthermore, the triple treatment increased DC infiltration in the MMTV-PyMT breast tumor model, leading to increased CD8+ T-cell infiltration and subsequent reductions of CD31+ and Ki67+ cells compared to the anti-PD-L1 Ab alone group or the SUP3 and anti-PD-L1 Ab combination group (Supplementary Fig S7C and D). This evidence concerns the gene CD8A and breast neoplasm.