Previous studies have indicated a close correlation between the degree of liver fibrosis and liver functional reserve [14, 15].Liver biopsy is considered the gold standard for detecting liver fibrosis, but non-invasive markers like APRI, FIB-4, Gamma-Glutamyl Transferase to Platelet Ratio (GPRI), and Albumin-Bilirubin index (ALBI) have shown good predictive ability [16–18]. The gene discussed is ALB; the disease is Hepatic fibrosis.