On the contrary, in glioblastoma (GBM), Du’s group et al. found that the micropeptide AF127577.4-ORF, encoded by lncRNA AF127577.4, was able to specifically interact with methyltransferase-like protein 3 (METTL3) and mitogen-activated protein kinase 1 (MAPK1/ERK2). This evidence concerns the gene MAP3K1 and glioblastoma.