Moreover, upregulated lncRNA Leucine Rich Repeat Containing 75 A Antisense RNA 1 (LRRC75A-AS1) in tumor tissues plays a role in epithelial-mesenchymal transition through the activation of IL-1β/mothers against decapentaplegic homolog 2/3 (smad2/3) signaling. This evidence concerns the gene IL1B and neoplasm.