RMDN3 and neuroblastoma: In Pr5 mice and human SH-SY5Y neuroblastoma cells, P301L expression reduces the number of ER–mitochondria contact sites by disrupting interactions between vesicle-associated membrane protein-associated protein B (VAPB) and protein tyrosine phosphatase-interacting protein 51 (PTPIP51), key tethering components of mitochondria-associated membranes (MAMs) (Szabo et al. 2023).