The abnormal redistribution of tau outside the axonal compartment is believed to be a distinctive feature associated with tauopathies such as Alzheimer ́s disease (AD), Progressive Supranuclear Palsy (PSP) and Pick’s disease (Martínez-Maldonado et al. 2021; Kawles et al. 2024). Here, MAPT is linked to Classical progressive supranuclear palsy.