SQSTM1 and neoplasm: Differential expression analysis between the tumor samples and their adjacent normal samples showed that p62 mRNA was upregulated in LIHC, KIRP, KICH, KIRC, READ, LUAD, and BRCA tumors (Fig. 2A), whereas it was downregulated in BLCA, PRAD, and PCPG (Fig. 2A).