Finally, we confirmed that the expression levels of the top immunosuppressive genes, EBAG9, PVR, TGFB1, B7-H3, TNFRSF14, and PD-L1, were significantly higher in the high-p62 group than in the low-p62 group in most cancers (Fig. 6C–H). The gene discussed is CD276; the disease is cancer.