Notably, the expression levels of IFIT3, SP140, GADD45B, MOV10, SMARCD3, JAK2, GADD45G, TDRD7, PCGF5, LMNB1, SAP30, and DTX3L were upregulated in the TB cohort, while SETD6, RSAD1, and TLE2 were downregulated. The gene discussed is TLE2; the disease is tuberculosis.