This showed that IFNg induced MHC-II upregulation in both NPM1 subtypes, and was associated with an increase in T cell sensitivity in the majority of samples from both subtypes (Supplementary Fig. 24), highlighting that T cell sensitivity in NPM1class I can be further increased by upregulating MHC-II, but also that the suppression of allogeneic T cells by NPM1class II AML cells occurs independently of MHC-II expression. Here, IFNG is linked to acute myeloid leukemia.