Multiplex immunofluorescence accordingly revealed that primary tumor tissues from mice treated with combination ICT showed a significant increase in tumor cells co-expressing GFP (marker of tumor cells) and myeloid markers such as S100A9 (Fig. 5f, g), CD68 (Supplementary Fig. S20), and F4/80 (Supplementary Fig. S21). The gene discussed is CD68; the disease is neoplasm.