OPN1MW and neoplasm: While neither CBD nor PPD alone showed strong antitumor effects,their coencapsulation in liposomes significantly inhibited tumor growthin 4T1 murine breast tumors, achieving an 82.2% inhibition rate (45mg/kg i.v.), outperforming injection of 8 mg/kg of Paclitaxel (64.4%).CBD-PPD liposomes administered orally (45 mg/kg) resulted in a significantlylower TIR (56.8%) than those administered intravenously.