HYOU1 and neoplasm: A significant overexpression (p < 0.0001) of ER chaperones was observed in aHGG (n = 99) compared to aNNB (n = 10) exceptfor GRP170 (Figure A–G) in the “Clinical Proteomic Tumor Analysis Consortium(CPTAC) GBM Discovery Study” data set. Similar results were observed for aHHG (n = 39)compared to aLGG (n = 9; ; ProteomeXChange Data set Identifier: PXD015545).Additionally, the heatmap (Figure H) showed an overall pattern in which a high relativeexpression (z-score) of one of the chaperones within a sample (eachcolumn) is associated with the elevated relative expression of theother chaperones.