IBSP and neoplasm: synthesized an alendronate(ALN)‐glucomannan conjugate that can target and eliminate TAMs via glucomannan and ALN, respectively.[271] Spontaneously formed ALN‐BSP (polysaccharide from Bletilla striata) NPs inhibited angiogenesis and tumor growth and prolonged animal survival with reduction of TAMs and activation of cytotoxic lymphocytes in S180 sarcoma‐bearing mice.