ERBB2 and breast carcinoma: Curdlan is a bacteria‐derived water‐insoluble linear β‐glucan exclusively composed of (1,3)‐β‐glucosidic linkages.[300, 301] In a study conducted by Nasrollahi et al., oxidized curdlan was fabricated into NPs by conjugating trastuzumab antibodies and DOX, followed by PEI coating to selectively deliver DOX to human epidermal growth factor receptor 2 (Her2)+ breast cancer.