ATRX and colorectal cancer: Research on colorectal cancer has revealed the dual regulatory role of the chromatin remodeling factor ATRX: The deletion of ATRX upregulates the function of p53 through the Daxx/MDM2 pathway (the expression of p21 is increased by 3.2 times), and at the same time inhibits the activation of the ATM/Chk2 pathway (the number of γ‐H2AX foci is reduced by 42%).