Similarly, expression of GBP1, NLRP3, and IL1B was downregulated in both HIF1‐KD and GBP1‐KD macrophages, while expression of ASC1 and HIF1A was upregulated in HIF1‐KD and GBP1‐KD macrophages, respectively, upon H37Rv infection, compared with controls (Figure S7). The gene discussed is NLRP3; the disease is infection.