A comprehensive non-invasive liver screen, including iron studies, immunoglobulins, alpha-1 antitrypsin, caeruloplasmin, amylase, hepatitis A, B, C, and E serologies, cytomegalovirus (CMV) and Epstein-Barr virus EBV) IgM, leptospira IgM, and autoimmune markers (antinuclear antibodies (ANA), anti-smooth muscle, anti-mitochondrial, liver-kidney microsomal type 1 (anti-LKM-1) antibodies, soluble liver antigen, and antineutrophil cytoplasmic antibodies (ANCA)) was unremarkable. The gene discussed is CD40LG; the disease is Hepatitis.