Laboratory tests indicated hemolytic anemia, thrombocytopenia, elevated LDH, and significant schistocytes (12%), but normal ANA and complement levels (Table 1). As she had high anti-FH autoantibody (>2,400 AU/mL), she was started on plasmapheresis and methylprednisolone pulse therapy. The gene discussed is FH; the disease is Thrombocytopenia.