We could perform a genetic test in only two out of five patients with anti-FH-associated HUS, where one had a heterozygous deletion and another had a homozygous deletion in CFHR3 (upstream region, exons 1, 2, 3, 4, 6, and intron 4), and CFHR1 (introns 1, 3, and exons 2, 4, 5, 6). This evidence concerns the gene CFHR3 and hemolytic-uremic syndrome.