AKT1 and hepatocellular carcinoma: Esmaeli and Dehghanpour Dehabadi recently highlighted the therapeutic potential of CBD in HCC by outlining several mechanisms of action including apoptosis, suppression of epithelial-mesenchymal transition (EMT), inhibition of the PI3K/AKT/mTOR pathway and enhancement of chemotherapy efficacy (Esmaeli and Dehghanpour Dehabadi 2025).