GFAP and early-onset autosomal dominant Alzheimer disease: Those biomarkers include inflammatory proteins, such as interleukin (IL)-6 and C-reactive protein (CRP)6,31,32, Alzheimer disease (AD) pathology markers6 and markers of neuronal injury, such as the neurofilament light chain (NEFL)9 and glial fibrillary acidic protein (GFAP)8.