Comparisons of tumor volume and weight among the groups showed that the TIMM23-KO + oe-NC/TIMM23-KO + oe-NC + Dox groups had significantly reduced tumor volume and weight compared to the TIMM23-WT + oe-NC/TIMM23-WT + oe-NC + Dox groups. This evidence concerns the gene TIMM23 and neoplasm.