In agreement with our transcriptomics data, we found markedly increased capacity of influenza-infected lung IL-18Rαhi CD8 T cells to produce IFNγ following stimulation with IL-12 and IL-18 overnight, while there was a clear lack of IFNγ production by lung IL-18Rαlo CD8 T cells following influenza virus infection (Fig. 5h). Here, IL18 is linked to influenza.