IGF2BP3 and familial pancreatic carcinoma: To further explore the effect of IGF2BP3 on the invasive and metastatic abilities of pancreatic cancer cells, we constructed control, Sh-IGF2BP3 (including two targets: Sh1 and Sh2), vector, and IGF2BP3 pancreatic cancer cell lines for a series of in vivo and in vitro experiments.