EMP1 and familial pancreatic carcinoma: The results showed that knockdown of EMP1 inhibited the migratory and invasive ability of pancreatic cancer cells, and at the same time, the influence of knockdown EMP1 could be restored the migratory and invasive ability of pancreatic cancer cells through exogenous expression of the wild type of EMP1 rather than the mutant type of the m6A locus in EMP1 (Fig. S2C, D).