AARS1 and gastric cancer: A recent study revealed that in gastric cancer (GC) cells, TEA domain family member (TEAD) and its coactivator Yes-associated protein (YAP) undergo lactylation, enhancing the stability and transcriptional activity of the YAP-TEAD complex, thus activating the expression of aminoacyl-tRNA synthetase 1 (AARS1), which, beyond its canonical role in protein synthesis, functions as a lactyltransferase.