Panel 3 complements Panels 1 and 2, as it was designed to assess LAG-3 expression on cytotoxic T cells (CD8+LAG-3+), macrophages (CD68+LAG-3+), NK cells (CD56+LAG-3+), Treg cells (FOXP3+LAG-3+) and tumour cells (SYN+LAG-3+). This evidence concerns the gene CD8A and neoplasm.