MKI67 and neoplasm: In the overall study cohort, a Log-rank test analysis indicated that a higher density of CD3+ T cells (HRlow vs high 5.15 [95% CI 1.250–21.184], p = 0.0233, Wald test) in tumours was associated with a longer PFS (Fig. 3A); a similar trend was detected CD3+Ki67+ (HRlow vs high 3.29 [95% CI 0.800–13.554], p = 0.0989, Wald test) (Fig. 3B).