FCN1 and lobular neoplasia: For FCN1, the GG genotype of rs2989727 was significantly less frequent among LN patients (3.0%) compared with those without LN (19.7%) (OR, 0.12 [95% CI, 0.03 to 0.54]; P = 0.001), whereas the AA genotype was notably more common among LN patients (48.5%) than non-LN patients (25.8%) (OR, 2.72 [95% CI, 1.47 to 5.03]; P = 0.001).